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Closed-angle (of pupillary-block) glaucoma is one
of many types of glaucoma. Often it can be cured through a procedure
called an iridotomy. To better understand closed-angle glaucoma and
its treatment, iridotomy (Figure 1), it is important to understand
the different factors which determine eye pressure.

Figure 1: In laser iridotomy, a small hole is placed in the
iris (the colored portion of the eye). In most patients, the iridotomy is
placed
in the upper portion of the iris and cannot be seen under the upper
eyelid.
What is eye pressure?
Aqueous humor (the nourishing fluid within the
front of the eye) leaves the eye through a tiny drain called the
trabecular meshwork (Figure 2).
Figure 2: Aqueous humor leaves the eye through a tiny
drain called the trabecular meshwork, which is located just in front of
the iris.
The trabecular meshwork is located on the side of
the eye, just in front of the iris (the part which gives an eye
color). Since the fluid is made just behind the iris, it must pass
between the iris and lens before leaving through the trabecular
meshwork (Figure 3a).
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| Figure 3a |
Figure 3b |
Figure 3a. (Normal Fluid Outflow) In
the normal eye, fluid passes between the iris and lens before
leaving through the trabecular meshwork in the front of the eye.
Figure 3b. (Pupillary-Block Glaucoma) In pupillary-block
glaucoma, a type of closed-angle glaucoma, the flow of fluid
between the iris and lens is blocked and the pressure builds in
the eye. As it rises, the iris is pushed forward.
The balance between how much fluid is made, and how much leaves
the eye, determines the pressure within the eye. All eyes have
measurable pressure. However, when the amount of aqueous humor
draining from the eye is reduced, the pressure within the eye can
increase. This high pressure often leads to glaucoma.
Although many people think of glaucoma as just one single
disease, in fact there are many different forms of glaucoma.
Differences depend upon where in the eye the blockage to the
drainage occurs. Both the border between the iris and lens as well
as the trabecular meshwork are areas where the flow of aqueous can
be limited, leading to increased eye pressure. One type of glaucoma,
pupillary-block glaucoma, occurs with the former. In this type of
closed-angle glaucoma, the flow of fluid between the iris and lens
is blocked (Figure 3b). It is called pupillary-block glaucoma
because the fluid is trapped behind the pupil.
Pupillary-Block Glaucoma
As many as 10% of all glaucoma patients in the
United States may have pupillary-block glaucoma. The blockage of
fluid flow between the iris and lens can cause the pressure behind
the iris to rise. As it rises, the iris is pushed forward. If it
moves forward enough, the iris can cover trabecular meshwork like a
rubber stopper in a drain.
Sometimes a patient is unaware of the pupillary-block. However,
the eye may become red. A patient also may experience headache or
pain, blurred vision, and halos around lights. Rarely, there is
nausea.
If there is sudden pupillary-block and if the eye is left
untreated, permanent damage can occur which can lead to blindness.
The sooner the blockade of fluid flow between the border of the
iris and lens is treated, the less damage occurs. Therefore, it is
desirable to treat this disease as early as possible.
The best treatment for pupillary-block glaucoma is to create a
hole in the iris (known as an iridotomy) (Figure 4A). The iridotomy
allows the flow of fluid to the front of the eye to be restored,
bypassing the pupil, the location of the blockade (Figure 4B).
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| Figure 4a |
Figure 4b |
Figure 4a. (Laser iridotomy) The hole
in the iris is known as an iridotomy. The iridotomy allows the
flow of fluid to the front of the eye to be restored.
Figure 4b. Final hole in iris to release pressure in eye.
With fluid passing through the iridotomy, the iris is no longer
pushed forward. Fluid can leave the eye through the trabecular
meshwork again.
How do lasers work to treat glaucoma?
Lasers deliver a type of light energy. This type
of light energy is similar to using a magnifying glass to harness
the energy of the sun to burn a hole in a piece of paper on a sunny
day. The magnifying glass needs to properly focus the light to
create a hole in the paper. Likewise, if the laser is not aimed
properly at the iris, there is no effect. In order to focus the
laser, your eye doctor uses an instrument called a slit-lamp.
This is the same instrument which is used to
routinely examine your eyes. Since this is actually a type of
microscope, the laser energy can be focused with extreme accuracy.
Several types of lasers can be used to treat pupillary-block glaucoma. The use of the argon laser to create an
iridotomy was accepted widely by 1980. Since then, another type of
laser, the neodymium: YAG laser, also has proven to be safe and
effective. Although there are some differences between these two
types of lasers, the use of one or another is best left to your
ophthalmologist.
How is laser iridotomy performed?
Before having an iridotomy, your ophthalmologist
may place some different types of drops on your eye. The first drop,
pilocarpine, will make your pupil smaller. This stretches and thins your iris, similar to
stretching out the top surface of a drum. By doing this, it is
easier for the laser to penetrate and make a hole in your iris. You
may be asked to continue using this eye drop for a few days
following the laser treatment. This medication may temporarily cause
blurred vision (especially at night) and also may give you a
brow-ache.
Another type of eye drop may be used within a few
hours of your laser treatment to prevent eye pressure from
increasing following laser treatment, or to treat and eye pressure
that already has increased. Still other eye drops may be used to
reduce inflammation.
The only kind of anesthesia required to perform a
laser iridotomy is an eye drop (Figure 5). This is the same type of
drop which your doctor places in your eye when the eye pressure is
measured. With the eye drop, the laser surgery should be painless.
You may see a bright light, like a photographer’s flash from a
close distance. Also, you may feel a pinch-like sensation.

Figure 5: The only anesthesia required to
perform a laser iridotomy is an eye drop.
Your doctor will next place a special contact
lens on your eye to focus the laser light upon the iris (Figure 6).
This lens keeps your eyelids separated so that you do not blink
during the treatment. This also reduces small eye movements so that
you do not have to worry about your eye moving during the treatment.
To protect the eye from being scratched by the contact lens, special
jelly is placed on its surface. This jelly may remain on your eye
for about 30 minutes, leading to blurred vision or a feeling of
heaviness.

Figure 6: A special contact is placed on
your eye to focus the laser upon the iris.
What to expect after an iridotomy.
After treatment, your doctor may ask you to stay
for a few hours to check your eye pressure and insure that it has
not increased.
When it is safe, you will be sent home and may be
asked to use eye drops. Your ophthalmologist will explain their use
and when you need to be examined again.
In general, there are no restrictions in activity
following the laser treatment. You can return to your normal daily
chores immediately. It is advisable to have someone drive you home
from your doctor’s office. You can expect some redness of the eye,
a sensitivity to light, and a scratchy sensation. All of these might
last for a period of days. You also might expect a small headache
later that day or night.
The chance of losing vision following a laser
procedure is extremely small. The main risks of a laser iridotomy
are that your iris might be difficult to penetrate, requiring more
than one treatment session. The other risk is that the hole in your
iris will close. This happens less than one-third of the time. Once
the hole stays open for six weeks, it is unlikely that it will close
in the future. In addition, you may still require medications, or
other treatments to keep your eye pressure sufficiently low. This
further treatment is necessary if there is damage to the trabecular
meshwork prior to the iridotomy or if you also have one of the other
types of glaucoma, in addition to the pupillary-block type.
Do not worry about the size of the hole in your
iris. Neither you nor your friends will notice it. It is usually
placed in a portion of the iris which is covered by your upper
eyelid. The size of the iridotomy is only that of a pin head.
Remember that the creation of a laser iridotomy
is both safe and effective. There are a few risks. The purpose of an
iridotomy is to preserve your vision, not to improve it.
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7150 Greenville Avenue, Suite 300
Dallas, TX 75231
Office: 214-360-0000
Fax: 214-360-0083
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